Atomic model of human cystic fibrosis transmembrane conductance regulator: Membrane-spanning domains and coupling interfaces

Structure of nucleotide‐binding domain 1 of the cystic fibrosis transmembrane conductance regulator

H.A. Lewis, Sean G. Buchanan, S.K. Burley et al. · The EMBO Journal · 2003 · 406 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

Phenylalanine-508 mediates a cytoplasmic–membrane domain contact in the CFTR 3D structure crucial to assembly and channel function

Adrian W.R. Serohijos, Tamás Hegedűs, Andrei A. Aleksandrov et al. · Proceedings of the National Academy of Sciences · 2008 · 377 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Impact of the ΔF508 Mutation in First Nucleotide-binding Domain of Human Cystic Fibrosis Transmembrane Conductance Regulator on Domain Folding and Structure

H.A. Lewis, Xun Zhao, Chi Chiu Wang et al. · Journal of Biological Chemistry · 2004 · 273 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Correctors Promote Maturation of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)-processing Mutants by Binding to the Protein

Ying Wang, Tip W. Loo, M. Claire Bartlett et al. · Journal of Biological Chemistry · 2007 · 130 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

A generalized analysis of hydrophobic and loop clusters within globular protein sequences

Richard Eudes, Khanh Le Tuan, J. Delettré et al. · BMC Structural Biology · 2007 · 53 citations · Full text

Life Sciences, Biochemistry, Bioinformatics +13