Tamás Hegedűs

Mechanism-based corrector combination restores ΔF508-CFTR folding and function

Tsukasa Okiyoneda, Guido Veit, Johanna F. Dekkers et al. · Nature Chemical Biology · 2013 · 386 citations · Full text

Protein Folding, Mechanism-based Corrector Combination, Molecular Biology +1

Phenylalanine-508 mediates a cytoplasmic–membrane domain contact in the CFTR 3D structure crucial to assembly and channel function

Adrian W.R. Serohijos, Tamás Hegedűs, Andrei A. Aleksandrov et al. · Proceedings of the National Academy of Sciences · 2008 · 376 citations · Full text

Membrane Structure, Proteinlipid Interaction, Cftr Assembly +17

Some gating potentiators, including VX-770, diminish ΔF508-CFTR functional expression

Guido Veit, Radu G. Avramescu, Doranda Perdomo et al. · Science Translational Medicine · 2014 · 283 citations · Full text

Domain Interdependence in the Biosynthetic Assembly of CFTR

Liying Cui, Luba A. Aleksandrov, Xiu-Bao Chang et al. · Journal of Molecular Biology · 2006 · 224 citations

Biomanufacturing, Bioengineering Model, Biofabrication +2

Membrane Topology and Glycosylation of the Human Multidrug Resistance-associated Protein

Éva Bakos, Tamás Hegedűs, Zsolt Holló et al. · Journal of Biological Chemistry · 1996 · 214 citations · Full text