The generation of a conditional Fmr1 knock out mouse model to study Fmrp function in vivo

Absence of expression of the FMR-1 gene in fragile X syndrome

Maura Pieretti, F Zhang, Ying‐Hui Fu et al. · Cell · 1991 · 1.5K citations

Fragile X Syndrome, Developmental Biology, Mendelian Disorder +11

Microarray Identification of FMRP-Associated Brain mRNAs and Altered mRNA Translational Profiles in Fragile X Syndrome

Victoria Brown, Peng Jin, Stephanie Ceman et al. · Cell · 2001 · 1.1K citations

Fragile X Syndrome, Genetic Disorder, Genetics +8

Fmr1 knockout mice: A model to study fragile X mental retardation

Cell · 1994 · 1K citations

Knockout Mouse, Molecular Neuroscience, Psychiatry +12

Abnormal dendritic spines in fragile X knockout mice: Maturation and pruning deficits

Thomas A. Comery, Jennifer B. Harris, Patrick J. Willems et al. · Proceedings of the National Academy of Sciences · 1997 · 1K citations · Full text

Fragile X Mental Retardation Protein Targets G Quartet mRNAs Important for Neuronal Function

Jennifer C. Darnell, Kirk B. Jensen, Peng Jin et al. · Cell · 2001 · 943 citations · Full text

Molecular Neuroscience, Developmental Biology, Genetic Disorder +13