Absence of expression of the FMR-1 gene in fragile X syndrome

Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome

Annemieke J.M.H. Verkerk, Maura Pieretti, James S. Sutcliffe et al. · Cell · 1991 · 3.5K citations

Life Sciences, Genetics, Molecular Genetics +12

Instability of a 550-Base Pair DNA Segment and Abnormal Methylation in Fragile X Syndrome

I. Oberlé, F. Rousseau, Dominique Heitz et al. · Science · 1991 · 1.5K citations

Life Sciences, Genetics, Molecular Genetics +16

Mapping of DNA Instability at the Fragile X to a Trinucleotide Repeat Sequence P(CCG) <i>n</i>

Eric J. Kremer, Melanie Pritchard, Michael Lynch et al. · Science · 1991 · 923 citations

Life Sciences, Genetics, Molecular Genetics +11

Fragile X Genotype Characterized by an Unstable Region of DNA

Shuancang Yu, Melanie Pritchard, Eric J. Kremer et al. · Science · 1991 · 799 citations

Life Sciences, Genetics, Molecular Genetics +16

Physical mapping across the fragile X: Hypermethylation and clinical expression of the fragile X syndrome

M.V. Bell, Mark C. Hirst, Yutaka Nakahori et al. · Cell · 1991 · 358 citations

Life Sciences, Genetics, Molecular Genetics +12