Concepedia

Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase

Calvin J. Kuo, Jongkyeong Chung, David Fiorentino, W. Michael Flanagan, John Blenis, Gerald R. Crabtree

Nature · 1992 · 600 citations · 19 references

DOI

Concepts

References

19

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

Jun S. Liu, Jesse D. Farmer, Willam S. Lane et al. · Cell · 1991 · 4.1K citations

, , +8

Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast

Joseph Heitman, N. Rao Movva, Michael N. Hall · Science · 1991 · 2K citations

, , +17

A receptor for the immuno-suppressant FK506 is a cis–trans peptidyl-prolyl isomerase

Matthew W. Harding, David Uehling, Stuart L. Schreiber · Nature · 1989 · 1.4K citations

, , +8

A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin

John J. Siekierka, Shirley H.Y. Hung, Martin Poe et al. · Nature · 1989 · 1K citations

, , +9

The Interleukin-2 T-Cell System: A New Cell Growth Model

Doreen A. Cantrell, Kendall A. Smith · Science · 1984 · 930 citations

, , +12