Variable contribution of cytochromes p450 2d6, 2c9 and 3a4 to the 4-hydroxylation of tamoxifen by human liver microsomes

The Carbon Monoxide-binding Pigment of Liver Microsomes

Tsuneo Omura, Ryo Sato · Journal of Biological Chemistry · 1964 · 11.8K citations · Full text

Life Sciences, Biochemistry, Chemistry +8

Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects

F. Peter Guengerich, Dong‐Hyun Kim, M. Iwasaki · Chemical Research in Toxicology · 1991 · 1.2K citations

Medicine, Oncology, Toxicology +8

Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions

Allan E. Rettie, Kenneth R. Korzekwa, Kent L. Kunze et al. · Chemical Research in Toxicology · 1992 · 602 citations

Medicine, Pharmacology, Toxicology +17

Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P-450IIE1

Raimund M. Peter, Ronald Boecker, Philippe Beaune et al. · Chemical Research in Toxicology · 1990 · 535 citations

Medicine, Pharmacology, Toxicology +11

A MONOHYDROXYLATED METABOLITE OF TAMOXIFEN WITH POTENT ANTIOESTROGENIC ACTIVITY

V. Craig Jordan, Margaret Collins, Linda Rowsby et al. · Journal of Endocrinology · 1977 · 503 citations

Life Sciences, Endocrinology, Pharmacology +15