Concepedia

Inhibitory effects of ZSTK474, a phosphatidylinositol 3-kinase inhibitor, on adjuvant-induced arthritis in rats

Kazuhiko Haruta, Shigeyuki Mori, Naoto Tamura, Asako Sasaki, Masakazu Nagamine, Shin‐ichi Yaguchi, Fumitaka Kamachi, Jumpei Enami, S Kobayashi, Takao Yamori,

Inflammation Research · 2012 · 19 citations · 34 references

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34

Specificity and mechanism of action of some commonly used protein kinase inhibitors

Stephen Davies, Helen Reddy, Matilde Caivano et al. · Biochemical Journal · 2000 · 4.1K citations · Full text

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Blockade of PI3Kγ suppresses joint inflammation and damage in mouse models of rheumatoid arthritis

Montserrat Camps, Thomas Rückle, Hong Ji et al. · Nature Medicine · 2005 · 751 citations

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Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3‐kinase inhibitors, wortmannin and LY294002.

G.J. Brunn, Josie M. Williams, Candace J. Sabers et al. · The EMBO Journal · 1996 · 723 citations · Full text

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Selective neutralization of prostaglandin E2 blocks inflammation, hyperalgesia, and interleukin 6 production in vivo.

Joseph P. Portanova, Y Zhang, Graham Anderson et al. · The Journal of Experimental Medicine · 1996 · 420 citations · Full text

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Antitumor Activity of ZSTK474, a New Phosphatidylinositol 3-Kinase Inhibitor

Shin‐ichi Yaguchi, Yasuhisa Fukui, Ichiro Koshimizu et al. · JNCI Journal of the National Cancer Institute · 2006 · 388 citations · Full text

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