Concepedia

New diarylamides and diarylureas possessing 8-amino(acetamido)quinoline scaffold: Synthesis, antiproliferative activities against melanoma cell lines, kinase inhibition, and in silico studies

Eun Jeong Koh, Mohammed I. El‐Gamal, Chang-Hyun Oh, So Ha Lee, Taebo Sim, Garam Kim, Hong Seok Choi, Jun Hee Hong, Sang‐gi Lee, Kyung Ho Yoo

European Journal of Medicinal Chemistry · 2013 · 28 citations · 21 references

DOI

Concepts

References

21

BAY 43-9006 Exhibits Broad Spectrum Oral Antitumor Activity and Targets the RAF/MEK/ERK Pathway and Receptor Tyrosine Kinases Involved in Tumor Progression and Angiogenesis

Scott M. Wilhelm, Christopher Carter, LiYa Tang et al. · Cancer Research · 2004 · 4K citations · Full text

, , +17

BRAF and RAS mutations in human lung cancer and melanoma.

Marcia S. Brose, Patrícia Volpe, Michael D. Feldman et al. · PubMed · 2002 · 1K citations

, , +17

Sorafenib in advanced melanoma: a Phase II randomised discontinuation trial analysis

Tim Eisen, T. Ahmad, Keith T. Flaherty et al. · British Journal of Cancer · 2006 · 636 citations · Full text

, , +15

Computational methods for the prediction of ‘drug-likeness’

David E. Clark, Stephen D. Pickett · Drug Discovery Today · 2000 · 573 citations

, , +14

Prognostic factors in 1,521 melanoma patients with distant metastases.

Andreas S. Barth, Leslie A. Wanek, D L Morton · PubMed · 1995 · 573 citations

, , +16