Isatin 1,2,3-triazoles as potent inhibitors against caspase-3

Click Chemistry: Diverse Chemical Function from a Few Good Reactions

Hartmuth C. Kolb, M. G. Finn, K. Barry Sharpless · Angewandte Chemie International Edition · 2001 · 13K citations

Pharmacy, Biochemistry, Chemistry +17

Click Chemistry: Diverse Chemical Function from a Few Good Reactions

Hartmuth C. Kolb, M. G. Finn, K. Barry Sharpless · Angewandte Chemie International Edition · 2001 · 9.3K citations · Full text

Pharmacy, Biochemistry, Chemistry +17

In Situ Click Chemistry:  Enzyme Inhibitors Made to Their Own Specifications

Roman Manetsch, Antoni Krasiński, Zoran Radić et al. · Journal of the American Chemical Society · 2004 · 420 citations

Pharmacy, Chemistry, Medicinal Chemistry +17

Potent and Selective Nonpeptide Inhibitors of Caspases 3 and 7 Inhibit Apoptosis and Maintain Cell Functionality

Dennis Lee, Scott A. Long, Jerry L. Adams et al. · Journal of Biological Chemistry · 2000 · 234 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +8

Rapid Discovery and Structure−Activity Profiling of Novel Inhibitors of Human Immunodeficiency Virus Type 1 Protease Enabled by the Copper(I)-Catalyzed Synthesis of 1,2,3-Triazoles and Their Further Functionalization

Matthew Whiting, Jonathan C. Tripp, Ying‐Chuan Lin et al. · Journal of Medicinal Chemistry · 2006 · 206 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +16