Zoran Radić

Click Chemistry In Situ: Acetylcholinesterase as a Reaction Vessel for the Selective Assembly of a Femtomolar Inhibitor from an Array of Building Blocks

Warren G. Lewis, Luke G. Green, Flavio Grynszpan et al. · Angewandte Chemie International Edition · 2002 · 734 citations

Form-fitting Chemistry, Bioorganic Chemistry, Molecular Biology +18

Three distinct domains in the cholinesterase molecule confer selectivity for acetyl- and butyrylcholinesterase inhibitors

Zoran Radić, Natilie A. Pickering, Daniel C. Vellom et al. · Biochemistry · 1993 · 437 citations

In Situ Click Chemistry:  Enzyme Inhibitors Made to Their Own Specifications

Roman Manetsch, Antoni Krasiński, Zoran Radić et al. · Journal of the American Chemical Society · 2004 · 418 citations

Lead Identification, Click Chemistry, Chemical Biology +18

In Situ Selection of Lead Compounds by Click Chemistry:  Target-Guided Optimization of Acetylcholinesterase Inhibitors

Antoni Krasiński, Zoran Radić, Roman Manetsch et al. · Journal of the American Chemical Society · 2005 · 338 citations

Lead Compounds, Combinatorial Chemistry, Bioorganic Chemistry +20

Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation

Yves Bourne, Hartmuth C. Kolb, Zoran Radić et al. · Proceedings of the National Academy of Sciences · 2004 · 329 citations · Full text