Nicorandil prevents endothelial dysfunction due to antioxidative effects via normalisation of NADPH oxidase and nitric oxide synthase in streptozotocin diabetic rats

Kenichi Serizawa, Kenji Yogo, Ken Aizawa, Yoshihito Tashiro, N Ishizuka

Cardiovascular Diabetology · 2011 · 64 citations · 52 references

DOIFull text

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Abstract

These results suggest that nicorandil improved diabetes-induced endothelial dysfunction through antioxidative effects by inhibiting NADPH oxidase and eNOS uncoupling.

References

52