An Anti-leukemic Single Chain Fv Antibody Selected from a Synthetic Human Phage Antibody Library

Isolation of high affinity human antibodies directly from large synthetic repertoires.

Andrew D. Griffiths, Samuel C. Williams, Oliver Hartley et al. · The EMBO Journal · 1994 · 974 citations · Full text

Pharmacy, Immunology, Molecular Biology +14

The Functional Expression of Antibody Fv Fragments in Ischhuchia coli: Improved Vectors and a Generally Applicable Purification Technique

Arne Skerra, Ilse Pfitzinger, Andreas Plückthun · Nature Biotechnology · 1991 · 245 citations

Pharmacy, Biomolecular Engineering, Molecular Biology +15

Rapid selection of cell subpopulation-specific human monoclonal antibodies from a synthetic phage antibody library.

John de Kruif, Leon W.M.M. Terstappen, Edwin Boel et al. · Proceedings of the National Academy of Sciences · 1995 · 217 citations

Pharmacy, Cell Biology, Immunology +17

Suppression and promotion of tumor growth by monoclonal antibodies to ErbB-2 differentially correlate with cellular uptake.

Esther Hurwitz, Ilana Stancovski, Michael Sela et al. · Proceedings of the National Academy of Sciences · 1995 · 147 citations

Medicine, Cancer Biology, Oncology +12

Immunotoxins for targeted cancer therapy

Robert J. Kreitman, Ira Pastan · Advanced Drug Delivery Reviews · 1998 · 136 citations

Medicine, Immunology, Oncology +12