Concepedia

Responsive microsecond-lifetime photoluminescent probes for analysis of protein kinases and their inhibitors

Marje Kasari, Kadri Ligi, J. A. Gareth Williams, Angela Vaasa, Erki Enkvist, Kaido Viht, Lars‐Olof Pålsson, Asko Uri

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · 2013 · 22 citations · 16 references

DOIFull text

Open access

Concepts

References

16

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

, , +14

Enzyme kinetics; behavior and analysis of rapid equilibrium and steady state enzyme systems

International Journal of Biochemistry · 1994 · 3K citations

, , +16

Evaluation of enzyme inhibitors in drug discovery. A guide for medicinal chemists and pharmacologists.

Robert A. Copeland · PubMed · 2005 · 1.1K citations

, , +17

Development and optimization of a binding assay for the XIAP BIR3 domain using fluorescence polarization

Zaneta Nikolovska‐Coleska, Renxiao Wang, Xueliang Fang et al. · Analytical Biochemistry · 2004 · 557 citations

, , +15

Kinase Drug Discovery – What’s Next in the Field?

Philip Cohen, Dario R. Alessi · ACS Chemical Biology · 2012 · 387 citations · Full text

, , +11