Concepedia

Acquired T-cell sensitivity to TRAIL mediated killing during HIV infection is regulated by CXCR4-gp120 interactions

Julian J. Lum, David Schnepple, Andrew D. Badley

AIDS · 2005 · 28 citations · 40 references

DOI

Abstract

These results indicate that chemokine receptor interactions regulate TRAIL receptor expression and provide an explanation for the acquired T cell sensitivity to TRAIL mediated killing death during HIV infection.

References

40

Frequent Detection and Isolation of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and at Risk for AIDS

Robert C. Gallo, Syed Zaki Salahuddin, Mikuláš Popovič et al. · Science · 1984 · 3.6K citations

, , +17

Tumoricidal activity of tumor necrosis factor–related apoptosis–inducing ligand in vivo

Henning Walczak, Robert E. Miller, K. Ariail et al. · Nature Medicine · 1999 · 2.5K citations

, , +9

The Receptor for the Cytotoxic Ligand TRAIL

Guohua Pan, Karen O’Rourke, Arul M. Chinnaiyan et al. · Science · 1997 · 1.8K citations

Control of TRAIL-Induced Apoptosis by a Family of Signaling and Decoy Receptors

James P. Sheridan, Scot A. Marsters, Robert Pitti et al. · Science · 1997 · 1.7K citations

, , +15

Osteoprotegerin Is a Receptor for the Cytotoxic Ligand TRAIL

John G. Emery, Peter McDonnell, Michael Brigham Burke et al. · Journal of Biological Chemistry · 1998 · 1.2K citations · Full text