Concepedia

A combinatorial F box protein directed pathway controls TRAF adaptor stability to regulate inflammation

Bill B. Chen, Tiffany A. Coon, Jennifer R. Glasser, Bryan J. McVerry, Jing Zhao, Yutong Zhao, Chunbin Zou, Bryon Ellis, Frank C. Sciurba, Yingze Zhang,

Nature Immunology · 2013 · 156 citations · 35 references

DOIFull text

Open access

Concepts

References

35

Structure of the Cul1–Rbx1–Skp1–F boxSkp2 SCF ubiquitin ligase complex

Ning Zheng, Brenda A. Schulman, Langzhou Song et al. · Nature · 2002 · 1.5K citations

, , +9

Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2

Sergio E. Alvarez, Kuzhuvelil B. Harikumar, Nitai C. Hait et al. · Nature · 2010 · 741 citations · Full text

, , +9

Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-κB signaling

Sivakumar Vallabhapurapu, Atsushi Matsuzawa, Weizhou Zhang et al. · Nature Immunology · 2008 · 608 citations · Full text

, , +13

TRAF6 Mediates Smad-Independent Activation of JNK and p38 by TGF-β

Motozo Yamashita, Károly Fátyol, Chaoyang Jin et al. · Molecular Cell · 2008 · 551 citations · Full text

, , +9

Control of the SCFSkp2–Cks1 ubiquitin ligase by the APC/CCdh1 ubiquitin ligase

Tarig Bashir, N. Valerio Dorrello, Virginia Amador et al. · Nature · 2004 · 501 citations

, , +8