Bill B. Chen

Lipopolysaccharide Primes the NALP3 Inflammasome by Inhibiting Its Ubiquitination and Degradation Mediated by the SCFFBXL2 E3 Ligase

SeungHye Han, Travis Lear, Jacob A. Jerome et al. · Journal of Biological Chemistry · 2015 · 192 citations · Full text

A combinatorial F box protein directed pathway controls TRAF adaptor stability to regulate inflammation

Bill B. Chen, Tiffany A. Coon, Jennifer R. Glasser et al. · Nature Immunology · 2013 · 152 citations · Full text

Inflammation, Cytokine, Signal Transduction +8

Dynamic regulation of cardiolipin by the lipid pump Atp8b1 determines the severity of lung injury in experimental pneumonia

Nancy B. Ray, Lakshmi Durairaj, Bill B. Chen et al. · Nature Medicine · 2010 · 145 citations · Full text

Acute Lung Injury, Inflammation, Dynamic Regulation +7

F-box protein FBXL19–mediated ubiquitination and degradation of the receptor for IL-33 limits pulmonary inflammation

Jing Zhao, Jianxin Wei, Rachel K. Mialki et al. · Nature Immunology · 2012 · 138 citations

Inflammation, Cytokine, Inflammatory Lung Disease +10

F-box protein FBXL2 targets cyclin D2 for ubiquitination and degradation to inhibit leukemic cell proliferation

Bill B. Chen, Jennifer R. Glasser, Tiffany A. Coon et al. · Blood · 2012 · 116 citations · Full text