Concepedia

Genome-wide retroviral insertional tagging of genes involved in cancer in Cdkn2a-deficient mice

Anders H. Lund, Geoffrey Turner, Alla Trubetskoy, Els Verhoeven, Ellen Wientjens, Danielle Hulsman, Robert G. Russell, Ronald A. DePinho, Jack Lenz, Maarten van Lohuizen

Nature Genetics · 2002 · 232 citations · 22 references

DOI

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22

Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a

Manuel Serrano, Athena W. Lin, Mila E. McCurrach et al. · Cell · 1997 · 5.1K citations · Full text

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Role of the INK4a Locus in Tumor Suppression and Cell Mortality

Manuel Serrano, Han‐Woong Lee, Lynda Chin et al. · Cell · 1996 · 1.6K citations · Full text

, , +16

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

Jacqueline J.L. Jacobs, Karin Kieboom, Silvia Marino et al. · Nature · 1999 · 1.6K citations

, , +13

The Two-Handed E Box Binding Zinc Finger Protein SIP1 Downregulates E-Cadherin and Induces Invasion

Joke Comijn, Geert Berx, Petra Vermassen et al. · Molecular Cell · 2001 · 1.4K citations · Full text

, , +7

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

Frédérique Zindy, Christine M. Eischen, David H. Randle et al. · Genes & Development · 1998 · 1.2K citations · Full text

, , +17