Engraftment of peripheral blood mononuclear cells from systemic lupus erythematosus and antiphospholipid syndrome patient donors into BALB‐RAG‐2^−/−IL‐2Rγ^−/− mice: A promising model for studying human disease

Abstract

We established a novel humanized SLE-DKO mouse exhibiting many of the immunologic and clinical features of human SLE.