Concepedia

Potent and selective inhibitors of the Abl-kinase: phenylamino-pyrimidine (PAP) derivatives

J. Zimmermann, Elisabeth Buchdunger, Helmut Mett, Thomas Meyer, Nicholas Lydon

Bioorganic & Medicinal Chemistry Letters · 1997 · 245 citations · 9 references

DOI

Concepts

References

9

Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr–Abl positive cells

Brian Druker, Shu Tamura, Elisabeth Buchdunger et al. · Nature Medicine · 1996 · 3.7K citations

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Tyrosine Kinase Activity and Transformation Potency of <i>bcr-abl</i> Oncogene Products

T G Lugo, Ann Marie Pendergast, Alexander J. Muller et al. · Science · 1990 · 1.3K citations

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Inhibition of the Abl protein-tyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative.

Elisabeth Buchdunger, J. Zimmermann, Helmut Mett et al. · PubMed · 1996 · 1.1K citations

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Acute leukaemia in bcr/abl transgenic mice

Nora Heisterkamp, Guido Jenster, Joanne ten Hoeve et al. · Nature · 1990 · 685 citations

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Selective Inhibition of Leukemia Cell Proliferation by BCR-ABL Antisense Oligodeoxynucleotides

Cezary Szczylik, Tomasz Skórski, Nicholas C. Nicolaides et al. · Science · 1991 · 348 citations · Full text

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