Organic & Biomolecular Chemistry · 2012 · 14 citations · 13 references
Life SciencesBiochemistryProtein BiochemistryStructural BiochemistryStructural BiologyCombinatorial Peptide SynthesisConformational ChangeMacromolecular StructureProtein ConformationProtein StructureSecondary StructureConformational StabilityPeptide FoldingPeptide Stability AnalysisPeptide Structure Analysis
A library of 14-helical hexa β(3)-peptides was synthesized in order to determine the influence of sequence variation as well as staple size and location on conformational stability. From this study we show that appropriately stapled hexa-β(3)-peptides can allow for a number of variations without significant perturbation of the 14-helix.
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Sylvia J. Degrado, Hirotake Mizutani, Amir H. Hoveyda · Journal of the American Chemical Society · 2001 · 250 citations
On the Antimicrobial and Hemolytic Activities of Amphiphilic <i>β</i> ‐Peptides
Per I. Arvidsson, Jens Frackenpohl, Neil S. Ryder et al. · ChemBioChem · 2001 · 98 citations