Concepedia

Inhibitors of the tyrosine kinase EphB4. Part 1: Structure-based design and optimization of a series of 2,4-bis-anilinopyrimidines

Catherine Bardelle, Darren A.E. Cross, Sara Davenport, Jason G. Kettle, Eun Jung Ko, Andrew G. Leach, Andrew Mortlock, Jon Read, Nicola Roberts, Peter Robins,

Bioorganic & Medicinal Chemistry Letters · 2008 · 55 citations · 12 references

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12

Molecular Distinction and Angiogenic Interaction between Embryonic Arteries and Veins Revealed by ephrin-B2 and Its Receptor Eph-B4

Hai U. Wang, Zhou‐Feng Chen, David J. Anderson · Cell · 1998 · 1.7K citations · Full text

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Symmetrical Mutant Phenotypes of the Receptor EphB4 and Its Specific Transmembrane Ligand ephrin-B2 in Cardiovascular Development

Sebastian S. Gerety, Hai U. Wang, Zhou‐Feng Chen et al. · Molecular Cell · 1999 · 708 citations · Full text

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Structural Basis for Autoinhibition of the EphB2 Receptor Tyrosine Kinase by the Unphosphorylated Juxtamembrane Region

Leanne Wybenga-Groot, Berivan Baskin, Siew Hwa Ong et al. · Cell · 2001 · 342 citations · Full text

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Hydrogen bonding. Part 9. Solute proton donor and proton acceptor scales for use in drug design

Michael H. Abraham, Philip P. Duce, David V. Prior et al. · Journal of the Chemical Society Perkin Transactions 2 · 1989 · 234 citations

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Eph B4 Receptor Signaling Mediates Endothelial Cell Migration and Proliferation via the Phosphatidylinositol 3-Kinase Pathway

Jena J. Steinle, Cynthia J. Meininger, Reza Forough et al. · Journal of Biological Chemistry · 2002 · 179 citations · Full text

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