Induction of the procarcinogen-activating CYP1A2 by a herbal dietary supplement in rats and humans

Analysis of 200 food items for benzo[a]pyrene and estimation of its intake in an epidemiologic study

Neely Kazerouni, Rashmi Sinha, Che-Han Hsu et al. · Food and Chemical Toxicology · 2001 · 522 citations

Nutrition, Dietary Exposure, Medicine +10

Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites

Marguerite A. Butler, Nicholas P. Lang, J.F. Young et al. · Pharmacogenetics · 1992 · 418 citations

Chemoprevention Strategy, Human Populations, Metabolomic Profiling +19

Rapid metabolic phenotypes for acetyltransferase and cytochrome P4501A2 and putative exposure to food-borne heterocyclic amines increase the risk for colorectal cancer or polyps.

Nicholas P. Lang, Marguerite A. Butler, Joyce Massengill et al. · PubMed · 1994 · 392 citations

Chemoprevention Strategy, Metabolomic Profiling, Pathology +17

Polymorphisms for aromatic amine metabolism in humans: relevance for human carcinogenesis.

Fred F. Kadlubar, Marguerite A. Butler, Keith R. Kaderlik et al. · Environmental Health Perspectives · 1992 · 230 citations · Full text

Genetics, Genetic Epidemiology, Metabolomic Profiling +21

Pan-fried meat containing high levels of heterocyclic aromatic amines but low levels of polycyclic aromatic hydrocarbons induces cytochrome P4501A2 activity in humans.

Rashmi Sinha, Nathaniel Rothman, Ellen Brown et al. · PubMed · 1994 · 191 citations

Dietary Exposure, Metabolomic Profiling, Food Toxicology +20