Regulation of Vascular Endothelial Growth Factor in endometrial tumour cells by resveratrol and EGCG

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Panu Jaakkola, David R. Mole, Ya‐Min Tian et al. · Science · 2001 · 5.5K citations

Life Sciences, Biochemistry, Molecular Biology +17

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

Patrick H. Maxwell, Michael S. Wiesener, Gin-Wen Chang et al. · Nature · 1999 · 5.2K citations

Medicine, Cancer Biology, Oncology +14

C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation

Andrew Epstein, Jonathan Gleadle, Luke A. McNeill et al. · Cell · 2001 · 3.3K citations · Full text

Life Sciences, Genetics, Molecular Biology +9

A Conserved Family of Prolyl-4-Hydroxylases That Modify HIF

Richard K. Bruick, Steven L. McKnight · Science · 2001 · 2.5K citations

Life Sciences, Biochemistry, Molecular Biology +16

HIF‐1 is expressed in normoxic tissue and displays an organ‐specific regulation under systemic hypoxia

Deborah Stroka, Tobias Burkhardt, Isabelle Desbaillets et al. · The FASEB Journal · 2001 · 720 citations · Full text

Medicine, Cell Biology, Molecular Biology +17