Effect of CYP2C9, VKORC1, CYP4F2 and GGCX genetic variants on warfarin maintenance dose and explicating a new pharmacogenetic algorithm in South Indian population

Reconstructing Indian population history

David Reich, Kumarasamy Thangaraj, Nick Patterson et al. · Nature · 2009 · 1.8K citations · Full text

Social Sciences, Anthropology, Demography +12

Estimation of the Warfarin Dose with Clinical and Pharmacogenetic Data

Teri E. Klein · New England Journal of Medicine · 2009 · 1.6K citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

Effect of <i>VKORC1</i> Haplotypes on Transcriptional Regulation and Warfarin Dose

Mark J. Rieder, Alex P. Reiner, Brian F. Gage et al. · New England Journal of Medicine · 2005 · 1.4K citations · Full text

Life Sciences, Genetics, Pharmacology +14

The impact of CYP2C9 and VKORC1 genetic polymorphism and patient characteristics upon warfarin dose requirements: proposal for a new dosing regimen

Elizabeth Sconce, Tayyaba Khan, Hilary Wynne et al. · Blood · 2005 · 947 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Randomized Trial of Genotype-Guided Versus Standard Warfarin Dosing in Patients Initiating Oral Anticoagulation

Jeffrey L. Anderson, Benjamin D. Horne, Scott M. Stevens et al. · Circulation · 2007 · 730 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +16