Response to Vitamin B12 and Folic Acid in Myalgic Encephalomyelitis and Fibromyalgia

Abstract

Patients with myalgic encephalomyelitis (ME, also called chronic fatigue syndrome) may respond most favorably to frequent vitamin B12 injections, in vital combination with oral folic acid. However, there is no established algorithm for individualized optimal dosages, and rate of improvement may differ considerably between responders.