Effects of polymorphisms of methionine synthase and methionine synthase reductase on total plasma homocysteine in the NHLBI Family Heart Study

Plasma homocysteine as a risk factor for vascular disease. The European Concerted Action Project.

Ian M. Graham · PubMed · 1997 · 1.8K citations

Medicine, Cardiology, Micronutrient Deficiency +14

Relation Between Folate Status, a Common Mutation in Methylenetetrahydrofolate Reductase, and Plasma Homocysteine Concentrations

Paul F. Jacques, Andrew G. Bostom, Roger R. Williams et al. · Circulation · 1996 · 1.4K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Determination of free and total homocysteine in human plasma by high-performance liquid chromatography with fluorescence detection

Atsushi Araki, Yoshiyasu Sako · Journal of Chromatography B Biomedical Sciences and Applications · 1987 · 1.1K citations

Natural Sciences, Biochemistry, Analytical Chemistry +8

A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes

Carol J. Boushey · JAMA · 1995 · 770 citations

Medicine, Nutrition, Nutritional Sciences +12

A Common Variant in Methionine Synthase Reductase Combined with Low Cobalamin (Vitamin B12) Increases Risk for Spina Bifida

Aaron Wilson, Robert W. Platt, Qing Wu et al. · Molecular Genetics and Metabolism · 1999 · 440 citations

Life Sciences, Biochemistry, Genetics +17