Concepedia

Methionine Synthase Function

Methionine Synthase Function is a biochemical process in vitamin B12 physiology that catalyzes the remethylation of homocysteine to methionine, distinguishing itself by its dependence on methylcobalamin as a cofactor and its critical role in one-carbon metabolism and DNA methylation.

726

Publications

42.6K

Citations

2.6K

Authors

855

Institutions

Publications per year

2017–2026

71

Parents

Publications

726

Hyperhomocysteinemia: An Independent Risk Factor for Vascular Disease

Robert Clarke, Leslie Daly, Killian Robinson et al. · New England Journal of Medicine · 1991 · 2.2K citations · Full text

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The natural history of homocystinuria due to cystathionine beta-synthase deficiency.

S. Harvey Mudd, Flemming Skovby, Harvey L. Levy et al. · PubMed · 1985 · 1.3K citations

, , +10

Metformin Retards Aging in C. elegans by Altering Microbial Folate and Methionine Metabolism

Filipe Cabreiro, Catherine Au, Kit‐Yi Leung et al. · Cell · 2013 · 965 citations · Full text

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How a Protein Binds B <sub>12</sub> : A 3.0 Å X-Ray Structure of B <sub>12</sub> -Binding Domains of Methionine Synthase

Catherine L. Drennan, Sha Huang, James T. Drummond · Science · 1994 · 593 citations

, , +17

The Quantitatively Important Relationship between Homocysteine Metabolism and Glutathione Synthesis by the Transsulfuration Pathway and Its Regulation by Redox Changes

Eugene V. Mosharov, Matthew R. Cranford, Ruma Banerjee · Biochemistry · 2000 · 524 citations

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1–5 of 726

Authors

2.6K

  1. RG
    Rowena G. Matthews

    University of Michigan, United States

    51 publications · 3.8K citations

    36

    h-index

  2. RB
    Ruma Banerjee

    University of Michigan, United States

    33 publications · 3K citations

    28

    h-index

  3. DS
    David S. Rosenblatt

    McGill University, Canada

    23 publications · 1.7K citations

    20

    h-index

  4. DW
    David Watkins

    McGill University, Canada

    12 publications · 1.1K citations

    12

    h-index

  5. AM
    Anne M. Molloy

    Trinity College Dublin, Ireland

    13 publications · 995 citations

    12

    h-index

1–5 of 2.6K

Institutions

855

  1. University of Michigan

    Ann Arbor, United States

    40 h-index

    194 publications

    16.4K citations

  2. McGill University

    Montreal, Canada

    25 h-index

    84 publications

    7.8K citations

  3. University of Nebraska–Lincoln

    Lincoln, United States

    24 h-index

    72 publications

    6.8K citations

  4. Trinity College Dublin

    Dublin, Ireland

    16 h-index

    57 publications

    10.6K citations

  5. National Institutes of Health

    Bethesda, United States

    16 h-index

    43 publications

    2.6K citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    14 h-index

    68 publications

    3.7K citations

  7. Radboud University Nijmegen

    Nijmegen, The Netherlands

    13 h-index

    51 publications

    2.8K citations

  8. Harvard University

    Cambridge, United States

    12 h-index

    38 publications

    2.1K citations

1–8 of 855

Venues

  1. Journal of Biological Chemistry

    JBC · 42 publications · 3.2K citations

    33

    h-index

  2. Biochemistry

    37 publications · 2.7K citations

    27

    h-index

  3. PubMed

    Repository · 29 publications · 2.8K citations

    20

    h-index

  4. Journal of Bacteriology

    JB · 22 publications · 1.1K citations

    19

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 17 publications · 1.8K citations

    17

    h-index

1–5