Wild-type microglia arrest pathology in a mouse model of Rett syndrome

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

Florent Ginhoux, Melanie Greter, Marylène Leboeuf et al. · Science · 2010 · 5.1K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

Ruthie E. Amir, Ignatia B. Van den Veyver, Mimi Wan et al. · Nature Genetics · 1999 · 5K citations

Life Sciences, Genetics, Molecular Genetics +9

Local self-renewal can sustain CNS microglia maintenance and function throughout adult life

Bahareh Ajami, Jami Bennett, Charles Krieger et al. · Nature Neuroscience · 2007 · 1.6K citations

Medicine, Neurobiology, Neuroscience +14

A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome

Jacky Guy, Brian Hendrich, Megan C. Holmes et al. · Nature Genetics · 2001 · 1.6K citations

Life Sciences, Genetics, Neuroscience +14

Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice

Richard Z. Chen, Schahram Akbarian, Matthew Tudor et al. · Nature Genetics · 2001 · 1.3K citations

Life Sciences, Neurobiology, Neuroscience +14