Metabolic pathway analysis and reduction for mammalian cell cultures—Towards macroscopic modeling

A general definition of metabolic pathways useful for systematic organization and analysis of complex metabolic networks

Stefan Schuster, David A. Fell, Thomas Dandekar · Nature Biotechnology · 2000 · 945 citations

Biology, Metabolic Network, Systems Biology +15

THE COVALENT STRUCTURE OF AN ENTIRE γG IMMUNOGLOBULIN MOLECULE

Gerald M. Edelman, Bruce A. Cunningham, W. Einar Gall et al. · Proceedings of the National Academy of Sciences · 1969 · 888 citations · Full text

Covalent Structure, Medicine, Natural Sciences +13

Superoxide Radical and Iron Modulate Aconitase Activity in Mammalian Cells

Paul R. Gardner, Inés Raineri, Lois B. Epstein et al. · Journal of Biological Chemistry · 1995 · 468 citations · Full text

Comparison of network-based pathway analysis methods

Jason A. Papin, Joerg Stelling, Nathan D. Price et al. · Trends in biotechnology · 2004 · 366 citations

Network Science, Engineering, Biological Network +8

Application of macroscopic principles to microbial metabolism

J. A. Roels · Biotechnology and Bioengineering · 1980 · 307 citations · Full text

Engineering, Microbial Physiology, Bioelectrochemical Reactor +21