The Synthesis and Antiviral Activity of 4-Fluoro-1-β-D-ribofuranosyl-1H-pyrazole-3-carboxamide

Abstract

A novel fluoropyrazole ribonucleoside has been shown to have significant anti-influenza activity in vitro. The compound is compared and contrasted with the structurally-related compound ribavirin in attempts to identify factors having significant bearing on the mode of action of both compounds.