Establishment of knockdown of superoxide dismutase 2 and expression of CYP3A4 cell system to evaluate drug-induced cytotoxicity

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

Tsutomu Shimada, Hiroshi Yamazaki, Mayumi Mimura et al. · Journal of Pharmacology and Experimental Therapeutics · 1994 · 2.8K citations

Medicine, Biochemistry, Pharmacology +15

Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice.

Russell M. Lebovitz, Henggui Zhang, Hannes Vogel et al. · Proceedings of the National Academy of Sciences · 1996 · 1K citations

Life Sciences, Neurobiology, Neuroscience +17

Intracellular hydrogen peroxide and superoxide anion detection in endothelial cells

Wayne O. Carter, Padma Kumar Naryanan, J. Paul Robinson · Journal of Leukocyte Biology · 1994 · 635 citations

Life Sciences, Biochemistry, Cell Biology +16

Regulation of manganese superoxide dismutase by lipopolysaccharide, interleukin-1, and tumor necrosis factor. Role in the acute inflammatory response.

Gary Visner, William C. Dougall, James M. Wilson et al. · Journal of Biological Chemistry · 1990 · 377 citations · Full text

Life Sciences, Cell Biology, Immunology +15

CYP3A4 drug interactions: correlation of 10 <i>in vitro</i> probe substrates

Kenworthy, Bloomer, Houston · British Journal of Clinical Pharmacology · 1999 · 337 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17