William C. Dougall

A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function

Dirk Anderson, Eugene Maraskovsky, William L. Billingsley et al. · Nature · 1997 · 2.3K citations

Inflammation, Cytokine, Signal Transduction +13

RANK is essential for osteoclast and lymph node development

William C. Dougall, Moira Glaccum, K Charrier et al. · Genes & Development · 1999 · 1.5K citations · Full text

Inflammation, Cytokine, Developmental Biology +15

The Novel Receptor TRAIL-R4 Induces NF-κB and Protects against TRAIL-Mediated Apoptosis, yet Retains an Incomplete Death Domain

Mariapia A. Degli‐Esposti, William C. Dougall, Pamela J. Smolak et al. · Immunity · 1997 · 816 citations · Full text

Trail-mediated Apoptosis, Signal Transduction, Signaling Pathway +10

RANK ligand mediates progestin-induced mammary epithelial proliferation and carcinogenesis

Eva González‐Suárez, Allison P. Jacob, Jon C. Jones et al. · Nature · 2010 · 583 citations

Tumor Biology, Mammary Gland, Breast Cancer +6

Denosumab, a Fully Human Monoclonal Antibody to RANKL, Inhibits Bone Resorption and Increases BMD in Knock-In Mice That Express Chimeric (Murine/Human) RANKL

Paul J. Kostenuik, Hung Q. Nguyen, James McCabe et al. · Journal of Bone and Mineral Research · 2008 · 428 citations