Tryptophan metabolism through the kynurenine pathway in rat brain and liver slices

Biostatistical Analysis.

Manning Feinleib, Jerrold H. Zar · Journal of the American Statistical Association · 1975 · 12.8K citations

Blood–Brain Barrier Transport of Kynurenines: Implications for Brain Synthesis and Metabolism

Shinsuke Fukui, Robert Schwarcz, Stanley I. Rapoport et al. · Journal of Neurochemistry · 1991 · 752 citations

Neurotransmitter, Social Sciences, Cerebral Vascular Regulation +19

3‐Hydroxykynurenine, an Endogenous Oxidative Stress Generator, Causes Neuronal Cell Death with Apoptotic Features and Region Selectivity

Shoki Okuda, Nobuyoshi Nishiyama, Hiroshi Saitō et al. · Journal of Neurochemistry · 1998 · 449 citations

Human macrophages convert <scp>l</scp>-tryptophan into the neurotoxin quinolinic acid

Melvyn P. Heyes, Kuniaki Saito, Sanford P. Markey · Biochemical Journal · 1992 · 448 citations · Full text

Immune Activation, Immunology, Neurotoxin Quinolinic Acid +18

1-methyl-dl-tryptophan, β-(3-benzofuranyl)-dl-alanine (the oxygen analog of tryptophan), and β-[3-benzo(b)thienyl]-dl-alanine (the sulfur analog of tryptophan) are competitive inhibitors for indoleamine 2,3-dioxygenase

Susan G. Cady, Masanori Sono · Archives of Biochemistry and Biophysics · 1991 · 281 citations

Medicinal Chemistry, Biochemistry, Medicine +9