Concepedia

Tryptophan Biosynthesis

Tryptophan Biosynthesis is a metabolic pathway within the shikimate pathway family that catalyzes the formation of the aromatic amino acid tryptophan from chorismate through a series of enzymatically regulated reactions distinct from those producing tyrosine or phenylalanine.

3.8K

Publications

213.6K

Citations

12.7K

Authors

2.6K

Institutions

Publications per year

2017–2026

552

Parents

Publications

3.8K

Inhibition of  T Cell Proliferation by Macrophage Tryptophan Catabolism

David H. Munn, Ebrahim Shafizadeh, John T. Attwood et al. · The Journal of Experimental Medicine · 1999 · 1.6K citations · Full text

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Gut microbes promote colonic serotonin production through an effect of short‐chain fatty acids on enterochromaffin cells

Christopher S. Reigstad, Charles E. Salmonson, John F. Rainey et al. · The FASEB Journal · 2014 · 1.3K citations · Full text

, , +17

A Role for Flavin Monooxygenase-Like Enzymes in Auxin Biosynthesis

Yunde Zhao, S. Christensen, Christian Fankhauser et al. · Science · 2001 · 1.2K citations

, , +17

Brain Serotonin Content: Physiological Regulation by Plasma Neutral Amino Acids

John D. Fernstrom, Richard J. Wurtman · Science · 1972 · 1.2K citations

, , +12

Tryptophan-derived Catabolites Are Responsible for Inhibition of T and Natural Killer Cell Proliferation Induced by Indoleamine 2,3-Dioxygenase

Guido Frumento, Rita Rotondo, Michela Tonetti et al. · The Journal of Experimental Medicine · 2002 · 1.1K citations · Full text

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1–5 of 3.8K

Authors

12.7K

  1. CY
    Charles Yanofsky

    Stanford University, United States

    145 publications · 9.4K citations

    60

    h-index

  2. EW
    Edith Wilson Miles

    National Institutes of Health, United States

    68 publications · 2.8K citations

    32

    h-index

  3. IP
    Irving P. Crawford

    Scripps Health, United States

    49 publications · 3.3K citations

    29

    h-index

  4. DF
    Dietmar Fuchs

    Innsbruck Medical University, Austria

    30 publications · 3.2K citations

    26

    h-index

  5. PP
    Paolo Puccetti

    University of Perugia, Italy

    20 publications · 3.3K citations

    20

    h-index

1–5 of 12.7K

Institutions

2.6K

  1. Stanford University

    Stanford, United States

    58 h-index

    318 publications

    22.7K citations

  2. National Institutes of Health

    Bethesda, United States

    40 h-index

    281 publications

    23.3K citations

  3. Harvard University

    Cambridge, United States

    37 h-index

    160 publications

    17.7K citations

  4. University of Illinois Urbana-Champaign

    Urbana, United States

    32 h-index

    114 publications

    7.4K citations

  5. University of California San Diego

    San Diego, United States

    31 h-index

    123 publications

    8.5K citations

  6. Yale University

    New Haven, United States

    31 h-index

    112 publications

    7.6K citations

  7. Inserm

    Paris, France

    31 h-index

    247 publications

    14K citations

  8. Centre National de la Recherche Scientifique

    Paris, France

    29 h-index

    173 publications

    8.9K citations

1–8 of 2.6K

Venues

  1. Journal of Biological Chemistry

    JBC · 213 publications · 13K citations

    62

    h-index

  2. Journal of Bacteriology

    JB · 205 publications · 10.4K citations

    57

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 86 publications · 9.8K citations

    54

    h-index

  4. Biochemistry

    135 publications · 6.5K citations

    48

    h-index

  5. Journal of Molecular Biology

    JMB · 76 publications · 5K citations

    45

    h-index

1–5