Concepedia

Rational design and in vitro and in vivo delivery of Dicer substrate siRNA

Mohammed Amarzguioui, Patric Lundberg, Edouard M. Cantin, James E. Hagstrom, Mark A. Behlke, John J. Rossi

Nature Protocols · 2006 · 131 citations · 32 references

DOI

Concepts

References

32

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Sayda M. Elbashir, Jens Harborth, Winfried Lendeckel et al. · Nature · 2001 · 9.4K citations

, , +7

RNA interference is mediated by 21- and 22-nucleotide RNAs

Sayda M. Elbashir, Winfried Lendeckel, Thomas Tuschl · Genes & Development · 2001 · 3.3K citations · Full text

, , +15

Asymmetry in the Assembly of the RNAi Enzyme Complex

Dianne S. Schwarz, György Hutvágner, Tingting Du et al. · Cell · 2003 · 2.8K citations · Full text

, , +12

Functional siRNAs and miRNAs Exhibit Strand Bias

Anastasia Khvorova, Angela Reynolds, Sumedha D. Jayasena · Cell · 2003 · 2.6K citations · Full text

, , +14

Rational siRNA design for RNA interference

Angela Reynolds, Devin Leake, Queta Boese et al. · Nature Biotechnology · 2004 · 2.1K citations

, , +12