FTO expression is regulated by availability of essential amino acids

A Common Variant in the <i>FTO</i> Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity

Timothy M. Frayling, Nicholas J. Timpson, Michael N. Weedon et al. · Science · 2007 · 4.4K citations · Full text

N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

Guifang Jia, Ye Fu, Xu Zhao et al. · Nature Chemical Biology · 2011 · 4K citations

Nuclear Rna, Natural Sciences, Genetics +10

An Integrated Stress Response Regulates Amino Acid Metabolism and Resistance to Oxidative Stress

Heather P. Harding, Yuhong Zhang, Huiquing Zeng et al. · Molecular Cell · 2003 · 3.3K citations · Full text

Reductive Stress, Biochemistry, Natural Sciences +9

The Obesity-Associated <i>FTO</i> Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase

Thomas Gerken, Christophe A. Girard, Yi‐Chun Loraine Tung et al. · Science · 2007 · 1.5K citations · Full text

Inactivation of the Fto gene protects from obesity

Julia Fischer, Linda Koch, Christian Emmerling et al. · Nature · 2009 · 937 citations

Obesity, Metabolic Syndrome, Metabolic Disorder +8