Inactivation of the Fto gene protects from obesity

Positional cloning of the mouse obese gene and its human homologue

Yiying Zhang, Ricardo Proenca, Margherita Maffei et al. · Nature · 1994 · 13.4K citations

Life Sciences, Genetics, Molecular Genetics +12

Serum Immunoreactive-Leptin Concentrations in Normal-Weight and Obese Humans

Robert V. Considine, Madhur K. Sinha, Mark L. Heiman et al. · New England Journal of Medicine · 1996 · 6.3K citations

Medicine, Endocrinology, Nutritional Sciences +7

A Common Variant in the <i>FTO</i> Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity

Timothy M. Frayling, Nicholas J. Timpson, Michael N. Weedon et al. · Science · 2007 · 4.5K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

A Genome-Wide Association Study of Type 2 Diabetes in Finns Detects Multiple Susceptibility Variants

Laura J. Scott, Karen L. Mohlke, Lori L. Bonnycastle et al. · Science · 2007 · 2.8K citations

Life Sciences, Endocrinology, Genetics +17

Derivation of completely cell culture-derived mice from early-passage embryonic stem cells.

András Nagy, Janet Rossant, Roland Nagy et al. · Proceedings of the National Academy of Sciences · 1993 · 2.4K citations

Life Sciences, Biology, Genetics +16