Enhanced Dendritic Cell Antigen Presentation in RNA-Based Immunotherapy

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.

Federica Sallusto, Antonio Lanzavecchia · The Journal of Experimental Medicine · 1994 · 5.2K citations · Full text

Life Sciences, Cell Biology, Immunology +17

Vaccination of melanoma patients with peptide- or tumorlysate-pulsed dendritic cells

Frank O. Nestlé, Selma Alijagic, Michel Gilliet et al. · Nature Medicine · 1998 · 2.9K citations

Medicine, Immunology, Oncology +14

Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products.

Federica Sallusto, Marina Cella, Carlo Danieli et al. · The Journal of Experimental Medicine · 1995 · 2.5K citations · Full text

Life Sciences, Cell Biology, Immunology +17

Vaccination of patients with B–cell lymphoma using autologous antigen–pulsed dendritic cells

Frank J. Hsu, Claudia Benike, Francesco Fagnoni et al. · Nature Medicine · 1996 · 1.8K citations

Medicine, Immunology, Oncology +16

Dendritic Cells: Unique Leukocyte Populations Which Control the Primary Immune Response

Derek N.J. Hart · Blood · 1997 · 1.5K citations

Life Sciences, Cell Biology, Immunology +15