The “survivin suppressants” NSC 80467 and YM155 induce a DNA damage response

Display and Analysis of Patterns of Differential Activity of Drugs Against Human Tumor Cell Lines: Development of Mean Graph and COMPARE Algorithm

Kenneth D. Paull, Robert H. Shoemaker, Louis Hodes et al. · JNCI Journal of the National Cancer Institute · 1989 · 969 citations

Medicine, Biostatistics, Oncology +16

Actinomycin and DNA transcription.

Henry M. Sobell · Proceedings of the National Academy of Sciences · 1985 · 567 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

YM155, a Novel Small-Molecule Survivin Suppressant, Induces Regression of Established Human Hormone-Refractory Prostate Tumor Xenografts

Takahito Nakahara, Masahiro Takeuchi, Isao Kinoyama et al. · Cancer Research · 2007 · 506 citations

Medicine, Oncology, Pharmacology +17

Multicenter Phase II Trial of YM155, a Small-Molecule Suppressor of Survivin, in Patients With Advanced, Refractory, Non–Small-Cell Lung Cancer

Giuseppe Giaccone, Petr Zatloukal, Jaromı́r Roubec et al. · Journal of Clinical Oncology · 2009 · 245 citations

Medicine, Oncology, Pharmacology +15

Generation of a drug resistance profile by quantitation of mdr-1/P-glycoprotein in the cell lines of the National Cancer Institute Anticancer Drug Screen.

Mauricio Muleiro Álvarez, K Paull, A Monks et al. · Journal of Clinical Investigation · 1995 · 219 citations · Full text

Medicine, Oncology, Pharmacology +14