Isao Kinoyama

YM155, a Novel Small-Molecule Survivin Suppressant, Induces Regression of Established Human Hormone-Refractory Prostate Tumor Xenografts

Takahito Nakahara, Masahiro Takeuchi, Isao Kinoyama et al. · Cancer Research · 2007 · 502 citations

Urology, Induces Regression, Chemoprevention Strategy +14

Broad spectrum and potent antitumor activities of YM155, a novel small‐molecule survivin suppressant, in a wide variety of human cancer cell lines and xenograft models

Takahito Nakahara, Aya Kita, Kentaro Yamanaka et al. · Cancer Science · 2010 · 165 citations

Chemoprevention Strategy, Xenograft Models, Pharmacotherapy +21

Sepantronium Bromide (YM155) induces disruption of the ILF3/p54nrb complex, which is required for survivin expression

Tomohiro Yamauchi, Naoto Nakamura, Masashi Hiramoto et al. · Biochemical and Biophysical Research Communications · 2012 · 71 citations

Signal Transduction, Immunology, Molecular Biology +6

Interleukin Enhancer-binding Factor 3/NF110 Is a Target of YM155, a Suppressant of Survivin

Naoto Nakamura, Tomohiro Yamauchi, Masashi Hiramoto et al. · Molecular & Cellular Proteomics · 2012 · 66 citations · Full text

Inflammation, Cancer Research, Transcriptional Regulation +13

YM155, a novel survivin suppressant, enhances taxane-induced apoptosis and tumor regression in a human Calu 6 lung cancer xenograft model

Takahito Nakahara, Kentaro Yamanaka, Shinji Hatakeyama et al. · Anti-Cancer Drugs · 2011 · 65 citations