Concepedia

Polymorphisms of PTPN11 Coding SHP-2 as Biomarkers for Ulcerative Colitis Susceptibility in the Japanese Population

Yukiko Narumi, Hajime Isomoto, Mizuho Shiota, Kayoko Sato, Shinji Kondo, Haruhisa Machida, Katsunori Yanagihara, Yohei Mizuta, Shigeru Kohno, Kazuhiro Tsukamoto

Journal of Clinical Immunology · 2009 · 27 citations · 25 references

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25

PD-L2 is a second ligand for PD-1 and inhibits T cell activation

Yvette Latchman, Clive R. Wood, Tatyana Chernova et al. · Nature Immunology · 2001 · 2.9K citations

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Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome

Marco Tartaglia, Ernest L. Mehler, Rosalie Goldberg et al. · Nature Genetics · 2001 · 1.7K citations

, , +11

SHP-1 and SHP-2 Associate with Immunoreceptor Tyrosine-Based Switch Motif of Programmed Death 1 upon Primary Human T Cell Stimulation, but Only Receptor Ligation Prevents T Cell Activation

Jens M. Chemnitz, Richard V. Parry, Kim E. Nichols et al. · The Journal of Immunology · 2004 · 1.2K citations · Full text

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Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia

Marco Tartaglia, Charlotte M. Niemeyer, Alessandra Fragale et al. · Nature Genetics · 2003 · 1K citations

, , +17

PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine

Taku Okazaki, Akito Maeda, Hiroyuki Nishimura et al. · Proceedings of the National Academy of Sciences · 2001 · 840 citations

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