Concepedia

Thymic stromal lymphopoietin stimulates the formation of eosinophil extracellular traps

M. Morshed, Shída Yousefi, Christina Stöckle, Hans‐Uwe Simon, Dagmar Simon

Allergy · 2012 · 146 citations · 34 references

DOI

Abstract

thymic stromal lymphopoietin directly stimulates eosinophils to produce EETs. Our observations link epithelial TSLP expression triggered by environmental factors with pathogen defense mechanisms involving eosinophils.

References

34

Human epithelial cells trigger dendritic cell–mediated allergic inflammation by producing TSLP

Vassili Soumelis, Pedro A. Reche, Holger Kanzler et al. · Nature Immunology · 2002 · 2.1K citations

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TSLP-activated dendritic cells induce an inflammatory T helper type 2 cell response through OX40 ligand

Tomoki� Ito, Yui-Hsi Wang, Omar Duramad et al. · The Journal of Experimental Medicine · 2005 · 1.1K citations · Full text

Cutting Edge: TLR2-Deficient and MyD88-Deficient Mice Are Highly Susceptible to <i>Staphylococcus aureus</i> Infection

Osamu Takeuchi, Katsuaki Hoshino, Shizuo Akira · The Journal of Immunology · 2000 · 1K citations

Viable neutrophils release mitochondrial DNA to form neutrophil extracellular traps

Shída Yousefi, Cristina C. Mihalache, Esther Kozlowski et al. · Cell Death and Differentiation · 2009 · 955 citations · Full text

, , +11

Catapult-like release of mitochondrial DNA by eosinophils contributes to antibacterial defense

Shída Yousefi, Jeffrey A. Gold, Nicola Andina et al. · Nature Medicine · 2008 · 934 citations

, , +9