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Discovery of imidazo[1,2-b]pyridazine derivatives as IKKβ inhibitors. Part 1: Hit-to-lead study and structure–activity relationship

Structure–activity RelationshipMedicinal ChemistryBiochemistryMedicineNatural SciencesRational Drug DesignHit-to-lead StudyDrug DevelopmentIkkβ InhibitorsPharmacologyPharmaceutical ChemistryInhibitory ActivityDrug Discovery