Vascular administration of adenoviral vector soaked in absorbable gelatin sponge particles (GSP) prolongs the transgene expression in hepatocytes

Sequestration of Adenoviral Vector by Kupffer Cells Leads to a Nonlinear Dose Response of Transduction in Liver

Nianjun Tao, Guangping Gao, Michael Parr et al. · Molecular Therapy · 2001 · 321 citations · Full text

Life Sciences, Immunology, Molecular Biology +14

Hepatic arterial infusion of a replication-selective oncolytic adenovirus (dl1520): phase II viral, immunologic, and clinical endpoints.

Tony Reid, E. Galanis, James L. Abbruzzese et al. · PubMed · 2002 · 310 citations

Medicine, Oncology, Pharmacology +17

Intra-arterial administration of a replication-selective adenovirus (dl1520) in patients with colorectal carcinoma metastatic to the liver: a phase I trial

T. Reid, E. Galanis, James L. Abbruzzese et al. · Gene Therapy · 2001 · 243 citations · Full text

Medicine, Clinical Pharmacokinetics, Oncology +16

Cochlear Gene Delivery through an Intact Round Window Membrane in Mouse

Jussi Jero, Anand N. Mhatre, Charles J. Tseng et al. · Human Gene Therapy · 2001 · 121 citations

Pharmacy, Biotechnology, Otolaryngology +17

Toxicological Comparison of E2a-Deleted and First-Generation Adenoviral Vectors Expressing <i>α</i> ₁ -Antitrypsin after Systemic Delivery

Wanda K. O’Neal, Heshan Zhou, Núria Morral et al. · Human Gene Therapy · 1998 · 120 citations

Pharmacy, Pharmacology, Toxicology +15