Peptidyl-transferase ribozymes: trans reactions, structural characterization and ribosomal RNA-like features

The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme

Cecilia Guerrier-Takada, Katheleen Gardiner, Norman R. Pace et al. · Cell · 1983 · 2.7K citations

Life Sciences, Biochemistry, Molecular Biology +14

The origin of the genetic code

Francis Crick · Journal of Molecular Biology · 1968 · 2.3K citations

Life Sciences, Evolutionary Biology, Genetics +12

Selection in vitro of an RNA enzyme that specifically cleaves single-stranded DNA

Debra L. Robertson, Gerald F. Joyce · Nature · 1990 · 1.3K citations

Life Sciences, Genetics, Molecular Biology +4

In vitro splicing of the ribosomal RNA precursor of tetrahymena: Involvement of a guanosine nucleotide in the excision of the intervening sequence

Thomas R. Cech, Arthur J. Zaug, Paula J. Grabowski · Cell · 1981 · 890 citations · Full text

Life Sciences, Genetics, Molecular Biology +8

Intermediate states in the movement of transfer RNA in the ribosome

Danesh Moazed, Harry F. Noller · Nature · 1989 · 739 citations

Life Sciences, Biochemistry, Molecular Biology +13