Agonist selectivity of glutamate receptors is specified by two domains structurally related to bacterial amino acid-binding proteins

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

Ulrich K. Laemmli · Nature · 1970 · 251K citations

Protein Assembly, Natural Sciences, Structural Proteins +8

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.8K citations

Cent Inhibition, Inhibitory Activity, Biochemistry +8

Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension

Robert M. Horton, Henry D. Hunt, Steffan N. Ho et al. · Gene · 1989 · 3.1K citations

Engineering, Hybridisation, Hybridization +13

Analysis of membrane and surface protein sequences with the hydrophobic moment plot

David Eisenberg, Erich M. Schwarz, M C Komaromy et al. · Journal of Molecular Biology · 1984 · 2.3K citations

Membrane Structure, Proteinlipid Interaction, Hydrophobic Moment Plot +9

Molecular cloning and characterization of the rat NMDA receptor

Koki Moriyoshi, Masayuki Masu, Takahiro Ishii et al. · Nature · 1991 · 1.8K citations

Molecular Pharmacology, Molecular Physiology, Signal Transduction +7