Concepedia

5-Lipoxygenase inhibition by N-hydroxycarbamates in dual-function compounds

Timothy A. Lewis, Lynn Bayless, A.J. Dipesa, Joseph Eckman, Michel Gillard, Lyn Libertine, Ralph T. Scannell, Donna M. Wypij, Michelle Young

Bioorganic & Medicinal Chemistry Letters · 2005 · 31 citations · 11 references

DOIFull text

Open access

Concepts

References

11

5-lipoxygenase inhibitory activity of zileuton.

G W Carter, Patrick Young, Daniel H. Albert et al. · Journal of Pharmacology and Experimental Therapeutics · 1990 · 420 citations

, , +13

Combined Antagonism of Leukotrienes and Histamine Produces Predominant Inhibition of Allergen-Induced Early and Late Phase Airway Obstruction in Asthmatics

A. Roquet, Barbro Dahlén, Maria Kumlin et al. · American Journal of Respiratory and Critical Care Medicine · 1997 · 311 citations

, , +14

Binding Characteristics of Cetirizine and Levocetirizine to Human H<sub>1</sub>Histamine Receptors: Contribution of Lys<sup>191</sup>and Thr<sup>194</sup>

Michel Gillard, Christy Van Der Perren, Nicole Moguilevsky et al. · Molecular Pharmacology · 2002 · 211 citations · Full text

, , +15

Antiasthmatic Effects of Mediator Blockade versus Topical Corticosteroids in Allergic Rhinitis and Asthma

Andrew M. Wilson, Linda Orr, Erika Sims et al. · American Journal of Respiratory and Critical Care Medicine · 2000 · 81 citations

, , +17

Regio- and Stereoselective Ring Openings of 3-Aza-2-oxabicyclo[2.2.1]hept-5-ene Systems with Copper Catalyst-Modified Grignard Reagents:  Application to the Synthesis of an Inhibitor of 5-Lipoxygenase

Mark J. Mulvihill, Marvin J. Miller · The Journal of Organic Chemistry · 2002 · 52 citations

, , +14