Concepedia

Covalent inhibition of recombinant human carboxylesterase 1 and 2 and monoacylglycerol lipase by the carbamates JZL184 and URB597

J. Allen Crow, Victoria Bittles, Abdolsamad Borazjani, Philip M. Potter, Matthew K. Ross

Biochemical Pharmacology · 2012 · 35 citations · 25 references

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25

Modulation of anxiety through blockade of anandamide hydrolysis

Satish Kathuria, Silvana Gaetani, Darren Fegley et al. · Nature Medicine · 2002 · 1.3K citations · Full text

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Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects

Jonathan Z. Long, Weiwei Li, Lamont Booker et al. · Nature Chemical Biology · 2008 · 938 citations · Full text

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A Physiologically Based Pharmacokinetic and Pharmacodynamic (PBPK/PD) Model for the Organophosphate Insecticide Chlorpyrifos in Rats and Humans

Charles Timchalk · Toxicological Sciences · 2002 · 281 citations · Full text

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Highly Selective Inhibitors of Monoacylglycerol Lipase Bearing a Reactive Group that Is Bioisosteric with Endocannabinoid Substrates

Jae Won Chang, Micah J. Niphakis, Kenneth M. Lum et al. · Chemistry & Biology · 2012 · 192 citations

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Identification and Characterization of Novel Benzil (Diphenylethane-1,2-dione) Analogues as Inhibitors of Mammalian Carboxylesterases

Randy M. Wadkins, Janice L. Hyatt, Xin Wei et al. · Journal of Medicinal Chemistry · 2005 · 186 citations · Full text

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