p53 protects against skin cancer induction by UV-B radiation

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

Lawrence A. Donehower, Michele Harvey, Betty L. Slagle et al. · Nature · 1992 · 4.7K citations

Medicine, Cancer Biology, Molecular Genetics +14

Germ Line p53 Mutations in a Familial Syndrome of Breast Cancer, Sarcomas, and Other Neoplasms

David Malkin, Frederick P. Li, Louise C. Strong et al. · Science · 1990 · 3.8K citations

Life Sciences, Genetics, Oncology +17

Tumor spectrum analysis in p53-mutant mice

Tyler Jacks, Lee Ann Remington, Bart O. Williams et al. · Current Biology · 1994 · 2.1K citations

Medicine, Cancer Biology, Oncology +12

A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma.

Douglas E. Brash, Jeffrey A. Rudolph, J A Simon et al. · Proceedings of the National Academy of Sciences · 1991 · 2K citations

Medicine, Genetics, Oncology +17

Sunburn and p53 in the onset of skin cancer

Annemarie Ziegler, Alan S. Jonason, David J. Leffellt et al. · Nature · 1994 · 1.5K citations

Medicine, Dermatology, Oncology +12