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Design and optimization of topical methotrexate loaded niosomes for enhanced management of psoriasis: Application of Box–Behnken design, in-vitro evaluation and in-vivo skin deposition study

NanomedicineEngineeringBox–behnken DesignTopical DrugClinical DermatologyDrug Delivery SystemsSkin PharmacologyBiomedical EngineeringTopical MethotrexateDermatologyMedicineEnhanced Management